Description:
BCR-ABL1 (p210) % IS Kit (Digital PCR Method) by Suzhou Sniper Medical Technologies Co. Ltd
The BCR-ABL1 (p210) % IS Kit (Digital PCR Method) is an innovative medical device by Suzhou Sniper Medical Technologies Co. Ltd. The central function of this kit lies in its ability to detect and quantify BCR-ABL1 gene transcripts in patients. The BCR-ABL1 gene is associated with certain types of leukemia, including Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL).
Utilizing state-of-the-art Digital PCR technology, this device offers exceptional precision and sensitivity when identifying and quantifying this specific oncogene. Compared to conventional quantitative PCR methods, digital PCR provides a higher degree of accuracy, enabling the identification of even minuscule changes in gene expression.
The importance of the BCR-ABL1 (p210) % IS Kit cannot be overstated for the monitoring of disease progression and response to treatment in patients with CML and ALL. Regular tracking of BCR-ABL1 gene expression using this kit can guide clinicians in adjusting treatment plans to achieve optimal patient outcomes.
In addition to accuracy, one of the noteworthy benefits of this kit is its usability. The kit has a straightforward design, facilitating efficient sample processing for medical professionals. With this reliable, user-friendly device, healthcare providers have a potent tool for managing CML and ALL in their patients.
Through the integration of cutting-edge technology and user-friendly design, Suzhou Sniper Medical Technologies Co. Ltd continues to provide valuable solutions for sophisticated clinical diagnostics and patient care.
How It Works:
Introduction to the BCR-ABL1 (p210) % IS Kit (Digital PCR Method)
The BCR-ABL1 (p210) % IS Kit, designed utilizing the advanced technique of Digital PCR, is a crucial device in the
field of medical genomics. This kit is specifically engineered for the detection of BCR-ABL1 gene rearrangements, which have been established to be key markers in certain myeloproliferative disorders.
How The Digital PCR Method Works
The foundation of Digital PCR's function resides within its ability to partition a sample of DNA into numerous individual, parallel PCR reactions. Some of these partitions may contain one DNA molecule, some may contain more, and others may have none.
To further clarify, when
PCR amplification is carried out after partitioning, end-point detection is executed. Either a single molecule in the partition is amplified to a detectable level or it is not; thus, defining the term 'digital'.
Understanding The Role of the BCR-ABL1 (p210) % IS Kit
The BCR-ABL1 (p210) % IS Kit utilizes this Digital PCR mechanism to measure the precise ratio of
BCR-ABL1 to
ABL1 gene sequences within patient samples. The determination of these gene rearrangements can assist in the
diagnosis and treatment of myeloproliferative disorders.
Application in Clinical Settings
In a clinical setting, medical practitioners utilize this kit for quantitative detection of the BCR-ABL1 gene in patients' chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). The BCR-ABL1 fusion gene, particularly the p210 isoform, is predominantly present in almost all cases of CML and a smaller percentage of ALL cases. In summary, the BCR-ABL1 (p210) % IS Kit (Digital PCR Method) can be a critcial tool in clinical diagnostics and patient monitoring throughout their therapeutic process.
Final Words
The innovative approach of this kit to gene rearrangement detection offers a more accurate and sensitive method over traditional techniques. With high precision and sensitivity, the BCR-ABL1 (p210) % IS Kit (Digital PCR Method) is an invaluable tool for healthcare providers aiming to deliver high-quality, personalized patient care in the realm of genetic disorders. This tool will continue to provide a critical component in the detection, monitoring, and overall management of myeloproliferative diseases.